Landmark Study Identifies New Genetic Risk Factors for Stroke


April 4, 2018

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A landmark international study of DNA samples from 520,000 individuals worldwide—including 67,000 affected individuals—identified 22 new genetic risk factors for stroke. Sudha Seshadri, M.D., of UT Health San Antonio, is senior co-author of this largest genetic study of stroke to date. Nature Genetics published the results online March 12.

Previously, only 10 genetic risk factors had been identified for stroke.

Dr. Seshadri, founding director of the Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases at UT Health San Antonio and holder of the university’s Robert Barker Distinguished University Chair, said the identification of genetic regions that are strongly correlated to stroke will increase potential targets for stroke drug development.


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